10 Recent
Medical Breakthroughs That Sound Like Science Fiction
1. The Bionic Eye
The “Argus
II” takes a video signal from a camera built into sunglasses and wirelessly
transmits that image to implants in the retinas of people who have lost their
vision. Though it’s been available in Europe since 2011, the U.S. Food and Drug
Administration (FDA) only approved the eye earlier this year. “This really is
like Star Trek technology,” Dr. Roizen says.
The system isn't perfect. It lets a blind person regain basic functions like
walking on a sidewalk without stepping off a curb, and distinguishing black
from white socks, but only lets you read one giant-sized word at a time on a
Kindle. Plus, as the retina itself heals over the implant, the quality of
vision decreases. The Argus II is currently only approved for people who have lost
their sight from retinal pigmentosis—which affects 1 in 4,000 Americans. But
the technology could soon help the more than 1.75 million people who suffer
from macular degeneration.
2. The Cancer Gene Fingerprint
Not all cancers are equally lethal—cancer in your prostate means a
longer survival rate than a malignancy in your brain, for example. But even
prostate cancer comes in multiple flavors ranging from manageable to very bad.
By analyzing the mutated genome of a tumor, doctors can now pinpoint whether a
cancer is sensitive to a certain chemotherapy, or one that doesn’t respond at
all to current treatments. Knowing the subtype might mean jumping directly to a
clinical trial that could save your life.
3. The
Seizure Stopper
For the 840,000 epileptics suffering from sudden, uncontrollable
seizures, the NeuroPace is like “a defibrillator for your brain,” Dr. Roizen
says. The system includes sensors implanted in the brain that can spot the
first tremors of an oncoming seizure. Then it sends electrical pulses that
counteract the brain's own haywire signals, stopping the seizure in its tracks.
Even more impressive: The NeuroPace can be fine-tuned by doctors based on its
performance. In the first year it was available, seizure episodes were reduced
by an average of 40 percent—but 2 years later, they dropped by 53 percent.
4. The
Hepatitis Cure
Until recently, treatment for hepatitis C fell into the
good-but-not-great category, with only around 70 percent of patients being
cured. And that was after as much as 48 weeks of a strict anti-viral drug
regimen, including injections of interferon—which causes a number of
debilitating side effects. But the new drug Sofosbuvir is a much more potent
killer of hep C, with success in as many as 95 percent of patients. Even more,
the medication only has to be administered for 12 weeks, sans interferon
injections.
For the 840,000 epileptics suffering from sudden, uncontrollable
seizures, the NeuroPace is like “a defibrillator for your brain,” Dr. Roizen
says. The system includes sensors implanted in the brain that can spot the
first tremors of an oncoming seizure. Then it sends electrical pulses that
counteract the brain's own haywire signals, stopping the seizure in its tracks.
Even more impressive: The NeuroPace can be fine-tuned by doctors based on its
performance. In the first year it was available, seizure episodes were reduced
by an average of 40 percent—but 2 years later, they dropped by 53 percent.
5. The Anesthesiologist's iPad
Surgeons may
get more glory, but anesthesiologists probably play the most vital role in
keeping you alive during surgery. They're the last face you see before you're
put into a medicated sleep so deep you don't even notice that your body is
being peeled open. Between keeping track of your heart rate, breathing, and
brain functions, an anesthesiologist also needs to be familiar with the ins and
outs of the procedure so they can adjust sedatives and painkillers—without
causing complications. The new “perioperative information management systems”
include software on touchscreen-enabled computers that can warn doctors if
things are going south, keep track of the surgeon's workflows, and document
every step of the procedure. All are essential when surgeries last up to 16 hours
and docs need to pass the reins to a fresh pair of eyes.
6. The
Fecal Transplant
The idea
of taking someone else's poop and giving it a new home in your own colon may
sound repulsive, but the treatment has proven remarkably effective in curing
infections of C.difficile—a nasty bacteria that
kills 15,000 people each year. Take heart: The digested food waste in feces
isn't itself the cure. You're simply gaining some of the helpful bacteria
living in the donor's gut—like a farmer choosing the hardiest crops to seed
next year's fields.
7. The
Heart-Saving Hormone
Around 1
in 4 people who are hospitalized for heart failure don't last much longer than
a year. But a new drug called Serelaxin has upped the odds of survival by as
much as 37 percent, according to a University of California, San Francisco
study. It's a synthetic version of the hormone relaxin, which is produced by
pregnant women to help with the increased stress carrying a fetus places on the
heart. “It not only opens up your blood vessels to supply your organs oxygen,
but it has anti-inflammatory properties,” Dr. Roizen says. Serelaxin's
life-saving potential is profound enough that in June, the FDA dubbed it a
“breakthrough therapy,” putting it on a faster track for approval in hospitals.
8. The
Robot Doctor
If you're
undergoing a colonoscopy, you'll want something to take the edge off (for
obvious reasons). But even a light sedative to help you snooze while doctors
spelunk your butt requires the presence of an anesthesiologist—which translates
to $1 billion in additional medical expenses, according to a study in theJournal of the American Medical Association. Enter the
Sedasys: a computer with an attachment on the IV that meters out the correct
amount of sedative and monitors vitals. It even includes an earpiece to wake
patients up if necessary. That allows docs to administer “light to moderate”
sedation on their own, with a single anesthesiologist supervising multiple
patients. “If Michael Jackson's doctor had this and knew how to use it, then
Michael Jackson would still be alive today,” says Dr. Roizen.
9. The
Better Heart-Attack Risk Test
Today you
get a cholesterol test to assess your risk of heart attack, but soon you'll be
more worried about your trimethylamine N-oxide (TMAO) levels. Why? People with
the highest levels of TMAO in their blood have 2.5 times the risk of a heart
attack compared to those with the lowest levels, according to a recent study in
the New England Journal of Medicine. TMAO is a compound
produced by intestine bacteria—yep, the same ones involved in fecal
transplants—after you eat choline, which is found in eggs, red meat, and
dairy.
10.
The Precision-Guided Cancer Treatment
The
difficult goal in any cancer treatment is to kill the tumor while leaving
healthy cells alone. Recently, a better understanding of what makes cancer
cells tick has allowed scientists to develop a class of drugs that pinpoint a
weakness in cancer's uncontrolled growth. For example, in lymphomas and
leukemias, scientists have determined that the growth is controlled by a
protein called Bruton's tyrosine kinase (BTK). After years of experimentation,
doctors developed a new drug called Ibrutinib that blocks BTK.
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